webmedi.blogspot.com

 BENAZEPRIL BRAND NAME:- BENZIL,Apriace,BENACE 5,10,20mg tab. Benazepril is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.  PHARMACODYNAMIC:- Benazepril, an angiotensin-converting enzyme (ACE) inhibitor, is a prodrug which, when hydrolyzed by esterases to its active Benazeprilat, is used to treat hypertension and heart failure, to reduce proteinuria and renal disease in patients with nephropathies, and to prevent stroke, myocardial infarction, and cardiac death in high-risk patients. Benazepril and Benazeprilat inhibit angiotensin-converting enzyme (ACE) in human subjects and animals . ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex.  MECHANISM OF ACTION:-  Benazepril...

 BENDROFLUMETHIAZIDE Brand name:- Bendrofulazide, Aprinox. BENDROFLUMETHIAZIDE is a type of medicine called a diuretic. It's used to treat high blood pressure (hypertension) and the build-up of fluid in your body (oedema). Diuretics are sometimes called "water tablets" because they make you pee more. This helps get rid of extra fluid in your body. Bendroflumethiazide is only available on prescription. It usually comes as tablets. It can also come as a liquid you swallow, but this has to be specially ordered.  PHARMACODYNAMIC:-  Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessari...

 BENIDIPINE BRAND NAME:- CARITEC 4,8mg tab, inzit,BENITOWA, Beniopack. BENIDIPINE is a long - acting DHP that owes its long duration of action to slow dissociation from the DHP receptor on the smooth muscle cells. Marketed only in India and Japan,it is indicated in hypertension and angina pectoris. PHARMACODYNAMIC:-  Benidipine reduces systolic and diastolic blood pressure as well as to present decreases in heart rate pulse after treatment. It is reported also a decrease urinary protein excretion and serum triglycerides. Different studies have shown benidipine anti-oxidative activity, stimulation of NO production, suppression of adhesion molecules expression, stimulation of osteoblast differentiation, suppression of the proliferation of vascular smooth muscle cells and mesangial cells, as well as myocardial protection. The enhancement of NO production is associated with the cardioprotective and anti artheriosclerotic effects of benidipine. MECHANISM OF ACTION:- Benidipine is a...

 BENOXINATE BRAND NAME:- BENDZON 0.4% eyedrops. BENOXINATE is also known as Oxybuprocaine. It is a good surface anaesthetic for the eye ; has little irritancy. A 0.4% solution rapidly produced corneal anaesthesia sufficient for tonometry without causing mydriasis or corneal damage. PHARMACODYNAMIC:-  BENOXINATE is a local anaesthetic. It may be less irritating than tetracaine, and the onset and duration of action are similar to tetracaine.  PHARMACOKINETICS:- Anaesthesia starts with a latency of 30 to 50 seconds and lasts for about 10 to 30 minutes, depending on perfusion. The drug is metabolised by esterases in blood plasma and liver. MECHANISM OF ACtion:- BENOXINATE binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses.  USED:-  A local anesthetic, which is used especially in op...

 BENSERAZIDE 

BENZALKONIUM CHLORIDE ( ZEPHIRAN)  BRAND NAME:- ZEPHIRAN It is highly soluble in water and alcohol. A 1:1000 solution is used for sterile storage of instruments and 1 in 5000 to 1 in 10,000 for douch, irrigation,etc. PHARMACODYNAMIC:- NOT AVAILABLE. MECHANISM OF ACTION:-  Benzalkonium chloride (BAC) is a wide spectrum quaternary ammonium antibacterial agent that has been used in various dental composites. It is cationically charged and induces antibacterial action through attraction to the negatively charged bacterial membrane. USED:-  Treating minor cuts, scrapes, and burns. Zephiran Solution is a topical antiseptic. It works by preventing infection. Miconazole topical is an antifungal medication SIDE EFFECTS:- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lip...

 BENZHEXOL (Trihexyphenidyl) BRAND NAME :- PACITANE,PARBENZ 2mg tab .  BENZHEXOL is an antispasmodic drug used to treat stiffness, tremors, spasms, and poor muscle control. It is an agent of the antimuscarinic class and is often used in management of Parkinson's disease.   PHARMACODYNAMIC:-  BENZHEXOL (Trihexyphenidyl) is an antimuscarinic indicated as an adjunct in the treatment of parkinsonism or as a treatment for drug-induced extrapyramidal symptoms.It has a long duration of action as it does not need to be given every day.It has a wide therapeutic window, with acute toxicity being non fatal in doses as high as 300 mg. Patients should have their iridocorneal angle examined before and intraocular pressure monitored during therapy.Patients should be counselled regarding the risk of anhidrosis and hyperthermia.  MECHANISM OF ACTION:-  BENZHEXOL is a non-selective muscarinic acetylcholine receptor antagonist but binds with higher affinity to the M1 sub...