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 BENZOYL PEROXIDE  BRAND NAME:-  PERSOL, PERNOX, BENZAC-AC 2.5% and 5%gel , PERSOL FORTE 10% cream with sulfur ppt.5%. BENZOYL PEROXIDE is one of the most effective and widely used in acne: gradually liberates oxygen (in the presence of water) which kills bacteria, especially anaerobic/ microaerophilic ones: used almost exclusively for acne because of its High efficacy against P.acnes and additional keratolytic and comedolytic properties. P.acenes  or other bacteria do not develop resistance to benzoyl peroxide. It induces mild desquamation the comedone caps are shed and production of irritant fatty acids in the sebum is reduced. Benzoyl peroxide is a mild irritant of the skin- burning and stinging sensation is often felt initially, localized erythema may occur . Most patients gradually developed tolerance to these actions; if not ,use should be discontinued. Avoid contact with eyes,lips , mucous membranes and denuded skin . It can bleach hair and coloured fabric....