webmedi.blogspot.com

 ATRACURIUM BRAND NAME:- TRACRIUM 10mg /ml inj in 2ml vial. PHARMACODYNAMIC:- ATRACURIUM is a skeletal muscle relaxant & neuromuscular blocking agent. It is an intermediate action. That act peripherally at neuromuscular junction/muscle fibres itself or centrally in the cerebrospinal axis to reduce muscle tone and/ or cause paralysis. The neuromuscular blocking agents are used primarily in conjunction with general anaesthetics to provide muscle relaxation for surgery, while centrally acting muscle relaxant are used mainly for painful muscle spasms and spastic neurological conditions. Atracurium  belongs to a group of medicines called muscle relaxants. It is used along with general anesthesia or sedatives to provide skeletal muscle relaxation during surgical procedures. It is also used to facilitate emergency airway management in patients in intensive care. MECHANISM OF ACTION:- Atracurium antagonizes the neurotransmitter action of acetylcholine by binding competitively with...

 ARTESUNATE + SULFADOXINE + PYRIMETHAMINE (AS-S/P) BRAND NAME:- ZESUNATE kit, MASUNATE kit,FALCIART kit  ARTESUNATE + SULFADOXINE + PYRIMETHAMINE (AS-S/P) ia an antimalarial Drug, groups of artemisinin Derivatives. This ACT has been adopted as the first line drug for uncomplicated falciparum malaria under the 'National antimalarial Drug policy ' of India,and has replaced CQ throughout the country. This does not imply that it is the most effective/ best ACT , because it is not effective against multidrug - resistance strains which are non responsive to S/P . However, treatment failures with AS-S/P ACT are mostly restricted to Northeast areas bordering Myanmar; while in rest of INDIA so far this ACT appears to be working satisfactorily with > 96% success rate. As such ,NVBDCP continues to use AS-S/P ACT as the first line therapy, including that during 2nd 3rd trimester of pregnancy. This ACT appears to produce fewer side effects than artesunate/ mefloquine. Private clinic, ho...

 AMPICILLIN BRAND NAME:-AMPICLIN,ROSCILLIN,BIOCILIN 250mg cap; 125,250mg/5ml dry syr; 100mg/ ml pediatric drops ; 250,500mg and 1.0 g per vial inj. AMPICILLIN is a extended spectrum penicillins of Aminopenicillins group drug . It is active against all organisms sensitive to PnG . In addition,many gram-negative bacilli,e g H. Influenzae, E.coli, Proteus salmonella Shigella and Helicobacter pylori are inhibited. However,due to wide- spread use ,many of these have developed resistance ; usefulness of the antibiotics has decreased considerably. AMPICILLIN is more active than PnG for Strep. Viridans , enterococci and Listeria ; equally active for pneumococci , gonococci and meningococci ( penicillin - resistant strains are resistant to ampicillin as well); but less active against other gram- postive cocci. Penicillinase producing Staph. are not affected, as are other gram-negative bacilli,such as Pseudomonas, Klebsiella, indole positive Proteus and anaerobes like Bacteroides fragilis. P...