Chlorzoxazone Brand name:- Flexon Mr 250mg + ibuprofen 400mg + paracetamol 325mg tab; Ultrazox 250mg + diclofenac 50mg + paracetamol 325mg tab; Mobizox. Chlorzoxazone is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. This improves pain and movement of muscles. Pharmacodynamic:- Chlorzoxazone is a centrally-acting agent for painful musculoskeletal conditions. Data available from animal experiments as well as human study indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multi synaptic reflex a.c. involved in producing and maintaining skeletal muscle spasm of varied etiology. The clinical result is a reduction of the skeletal muscle spasm with relief of pain and increased mobility of the involved muscles. Mechanism of action:- Chlorzoxazone inhibits degranulation of mast cells, subsequently prevent...
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