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 BETAMETHASONE DISPROPORTIONATE BRAND NAME:- DIPROLENE oint  BETAMETHASONE DIPROPIONATE is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities. It is applied as a topical cream, ointment, lotion or gel . PHARMACOKINETICS:- Absorption of topical corticosteroids depends on several factors such as the vehicle, or delivery system used by the drug, the integrity of the epidermal barrier, and whether or not an occlusive bandage is used in combination with the drug.The absorption of topical betamethasone dipropionate is theoretically minuscule; however, if absorbed it follows the same pharmacokinetic profile that is typical of systemic corticosteroids. It is metabolized primarily by the liver by hydrolysis to its metabolites B17P (primary) and betamethasone and the 6β-hydroxy derivatives of those metabolites, and it is excreted primarily by the kidneys. MECHANISM OF ACTION:-  Betamethasone dipropionate binds to specific intracellular glucocorticoid re...