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 ARIPIPRAZOLE BRAND NAME:- ABILIFY ,ARIPRA,ARILAN,BILIEF 10,15mg tabs, ARIVE 10,15,20,30mg tabs. ARIPIPRAZOLE is an antipsychotics is unique in being a partial agonist at D2 and 5-HT 1À receptor, but antagonist at 5- HT2 receptor. The high affinity but low intrinsic activity of aripiprazole for D2 receptors impedes dopaminergic transmission by occupying a large fraction of D2 receptors but activating them minimally . It is not sedation,may even cause insomnia. PHARMACODYNAMIC:- Aripiprazole has high affinity for serotonin type 2 (5HT2), dopamine type 2 (D2), alpha1 and 2 adrenergic, and H1 histaminergic receptors. It also acts on a number of other receptors with lower affinity. The exact method by which aripiprazole's action on these receptors translates to a clinically relevant effect is not yet known. MECHANISM OF ACTION:- The antipsychotic action of aripipra byzole is likely due to the agonism of D2 and 5-HT1A receptors though the exact mechanism has not been defined. Some adver...