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 ARTEMISININ  BRAND NAME:- no specific brand available. ARTEMISININ is the active principal of the plant artemisia annua used in Chinese traditional medicine as ' Quinghaosu '  . It is a sesquiterpine lactones endoperoxide active against P. Falciparum resistant to all other antimalarial drugs as well as sensitive strains and other malarial species. MECHANISM OF ACTION:-  Of artemisinin is not definitely known. The endoperoxide brige in its molecules appears to interact with haeme in the parasite. Ferrous iron- mediated clevage of the brige release a highly reactive free radicals species that binds to membrane proteins, causes lipid peroxidation , damages endoplasmic reticulum ,and ultimately result in lysis of the parasite. Another line of evidence has shown that the artemisinin free radicals specifically inhibits a plasmodial sarcoplasma - endoplasmic calcium ATPase labelled 'PF ATP6'. Pharmacodynamic:-  🚫 Not available. Pharmacokinetics:- poor pharmacokinetic...