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 ALPROSTADIL BRAND NAME:- muse,prostin,Edex & etc. ALPROSTADIL  is used to treat erectile dysfunction (impotence) and to help diagnose certain causes of this disorder. Alprostadil is also used to improve blood flow in newborn babies with heart problems.  This medication guide addresses only the adult male use of alprostadil in erectile disorders. MECHANISM & PHARMACOLOGICAL ACTION:- Alprostadil (PGE1) injected  directly into the corpus cavernous using a fine needle produces erection lasting 1-2 hours to permit intercourse. Alprostadil injections are less painful than papaverine,but local tenderness may occur. Penile fibrosis and priapism are rare. It is now the most commonly used drug in patients not responding to PDE-5 inhibitors,such as neurogenic and psychogenic ED. Alprostadil relaxes blood vessels and muscles in the penis which increases blood flow, causing an erection. Alprostadil may also be used for purposes not listed in this medication guide. USES ...