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 BRINZOLAMIDE BRAND NAME:- azopt, Brinzox , Brinolar  BRINZOLAMIDE is a carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. PHARMACODYNAMIC:- Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion and thus lowers the intraocular pressure in the anterior chamber, presumably by reducing the rate of formation of bicarbonate ions with subsequent reduction in sodium and fluid transport; this may alleviate the effects of open-angle glaucoma.   PHARMACOKINETICS:- Brinzolamide is a topical carbonic anhydrase inhibitor which reduces the production of aqueous humor in the ciliary body, thereby reducing intra-ocular pressure. It is formulated as an ophthalmic suspension. The pharmacokinetics of ocular suspensions is not well understood.  MECHANISM OF ACTION:- Brinzolamide is a highly specific inhibitor of CA-II, which is the main CA isoenzyme involved in the ...