Skip to main content

Posts

Showing posts with the label calcitriol mechanism of action

Calcitriol Uses, Side Effects, and More

 Calcitriol  Brand name:- Caltrol, Rolsical ,Rocaltrol 0.25ùg cap. Calcibest 1ml aqueous inj; Calcitriol is the active form of Vitamin D. It raises Vitamin D levels in your blood. This in turn raises calcium levels in your blood by helping you absorb more calcium from your intestine. Pharmacodynamic:- Calcitriol is a biologically active calcitrophic hormone with anti-osteoporotic, immunomodulatory, anticarcinogenic, antipsoriatic, antioxidant, and mood-modulatory activities. Its main sites of action are the intestine, bone, kidney and parathyroid hormone Label. Calcitriol is a ligand for the vitamin D nuclear receptor, which is expressed in, but not limited to, gastrointestinal (GI) tissues, bones, and kidneys . As an active form of vitamin D3, calcitriol elevates the plasma levels of calcium by stimulating intestinal calcium uptake, increasing reabsorption of calcium by the kidneys, and possibly increasing the release of calcium from skeletal stores. The duration of pharmacol...