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 Carboplatin Brand name:-   Oncocarbin 150mg inj. ,  Kemocarb150,450 mg/Vail inj. 400mg/m² .  Carboplatin is an anti-cancer medication . It is a less reactive second generation platinum compound that is better tolerated and has a toxicity profile different from Cisplatin.It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication. Pharmacodynamic:-  Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Carboplatin has a long duration of action as it is given every  weeks, and a narrow therapeutic index. Patients should be counselled regarding bone marrow suppression and anemia. Pharmacokinetics:- After a 1 hour infusion of carboplatin, the blood levels of total platinum and free platinum reduce in a biphasic manner. For the free platinum, the first phase of the half life (when the drug achieves half its plasma concentration) is ar...