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 ADRIAMYCIN (DOXORUBICIN) BRAND NAME:- DAUNOCIN,DAUNOMYCIN 20mg/vial inj. , ADRIAMYCIN, DOXORUBICIN,ONCODRIA 10 mg ,50mg per vial inj. ADRIAMYCIN are also known as doxorubicin , doxorubicin are  anthracycline antibiotics having antitumour activity, isolated from cultures of Streptomyces peucetius var. caesius. Doxorubicin binds to nucleic acids, presumably by specific intercalation of the planar anthracycline nucleus with the DNA double helix. ACTIONS:- These are anthracycline antibiotics having antitumour activity. However, utility of daunorubicin is limited to acute myeloid as well as Lymphoblastic leukaemia (in which it is highly active), while doxorubicin,in addition,is effective in many solid tumors,such as breast, thyroid,ovary, bladder and lung cancer,scrcomas and neuroblastoma.  They intercalate between DNA strands and block DNA as well as RNA synthesis. They are also capable of causing breaks in DNA strands by activating topoisomerase -2 and generation quinone ty...