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 ARGATROBAN BRAND NAME:- no specific brand available. ARGATROBAN is a synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use. PHARMACOLOGICAL ACTION:- Argatroban is a synthetic nonpeptide compound which binds reversibly to the catalytic site of thrombin,but not to the substrate recognition site. As such ,it produces a rapid and short lasting antithrombin action .That is approved in the USA, the EU and Japan for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT), and for anticoagulation of HIT patients undergoing PCI.  MECHANISM OF ACTION:- Argatroban exerts its anticoagulant effects by inhibiting thrombin-catalyzed or -induced reactions, including fibrin formation; activation of coagulation factors V, VIII, and XIII; protein C; and platelet aggregation. Administered by i.v . Infusion,it can be used in place of lepirudin for short - term indication in patients with heparin-induce...