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BRAN ( Dietary fibres)used, Side dose, pharmacodynamic & mechanism of action......

 BRAN ( Dietary fibre) BRAND NAME:- many local brands available in India 🇮🇳. BRAN is a dietary fibre consists of unabsorbable cell wall and other constituents of vegetables food — cellulose, lignins,gums,pectins, glycoproteins and others polysaccharides. PHARMACOLOGICAL & MECHANISM OF ACTION:-  Bran is the residual product of flour industry which consists of ~40% dietary fibre. It absorbs water in the intestine,swells, increases water content of faeces — softens it and facilitates colonic transit. Osmotically active products may be formed in the colon by bacterial degradation of pectins, gums etc. Which act to retain water. Dietary fibre supports bacterial growth in colon which contributes to the faecal mass. Certain Dietary fibres (gums, lignins, pectins) bind bile acids and promote their excretion in faeces » degradation of cholesterol in liver is enhanced » plasma LDL- cholesterol may be somewhat lowered. Increased intake of dietary fibres is the most appropriate meth...