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Showing posts with the label vitamin D³ used

Cholecalciferol ( vit D³) used, Side, Doses, mechanism of action & more

Cholecalciferol ( vit D³) Brand name:-  Arachitol 300000 IU ( 7.5 mg) & 600000 IU ( 15mg) per ml inj. , Calcirol , Calcibest sachets 60000 IU in 1 g granules.  Vitamin D3 is a form of vitamin D. It raises vitamin D levels in your blood. This in turn raises calcium levels in your blood by helping you absorb more calcium from food. Pharmacodynamic:- The in vivo synthesis of the predominant two biologically active metabolites of vitamin D occurs in two steps. The first hydroxylation of vitamin D³ cholecalciferol (or D2) occurs in the liver to yield 25 -hydroxyvitamin D while the second hydroxylation happens in the kidneys to give 1, 25- dihydroxyvitamin D . These vitamin D metabolites subsequently facilitate the active absorption of calcium and phosphorus in the small intestine, serving to increase serum calcium and phosphate levels sufficiently to allow bone mineralization . Conversely, these vitamin D metabolites also assist in mobilizing calcium and phosphate from bone and...