AMETHOCAINE ( TETRACAINE ) BRAND NAME:-ANETHANE powder for solution,1% ointment. Tetracaine is a local ester anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures. Pharmacodynamic:- Not 🚫 AVAILABLE Mechanism of action:- A highly lipid - soluble PABA ester ,more potent and more toxic due to slow hydrolysis by plasma pseudocholinesterase . It is both surface and conduction block anaesthetic, but its use is restricted to topical application to the eye,nose, throat,tracheobronchial tree and rarely for spinal or caudal anaesthesia of long duration. Though it is slow acting, absorption from tracheobronchial spray is very fast and blood concentrations approach those attained after i.v. injection. USED:- Use in emergency departments, especially for starting intravenous lines in children, in view of its analgesic and cost-saving properties. Tetracaine is the T in TAC, a mixture of 5 to 12% tetracaine, 0.05% adrenaline, and ...
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