AMPHETAMINES BRAND NAME:- ADDERALL,ADZEnys etc.. many brands available in India. Amphetamine is a powerful stimulator of the central nervous system . The central actions of amphetamines are largely medicated by release of NA from adrenergic neurones in the brain. Indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). PHARMACODYNAMIC ACTION:- These are synthesis compounds having a Pharmacological profile similar to ephedrine; it has been demonstrated that amphetamine augments the concentration of noradrenaline in the prefrontal cortex and dopamine in the striatum on a dose and time-dependent manner. The indistinct release of neurotransmitters which include adrenaline is known to produce cardiovascular side effects. There are old reports of a cognitive enhancement related to the administration of amphetamine in which improvements in intelligence test scores were reported. In ADHD, amphetamine has been largely showed to produce remarkable improvements i...
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