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 BICALUTAMIDE BRAND NAME:- BIPRIOSTA ,CALUTIDE ,TABI 50mg tab. BICALUTAMIDE is more potent and longer acting ( t½ 6 days ) congeners of flutamide is suitable for once daily administration in metastatic carcinoma of prostate as a component of CAB therapy. When used along with a GnRH agonist or castration, 50mg affords marked relief in bone pain and other symptoms due to the metastasis .  PHARMACODYNAMIC:- Bicalutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Bicalutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Bicalutamide blocks the action of androgens of adrenal and testicular origin which stimulate the growth of normal and malignant prostatic tissue. Prostate cancer is mostly androgen-dependent and can be treated with surgical or chemical castration. To date, antiandrogen monotherapy has not consistently been shown ...