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ANTHRAQUINONES

 ANTHRAQUINONES BRAND NAME:- GLAXENNA 11.5 mg tab; PURSENNID 18mg tab; SOFSENA 12mg tab. ANTHRAQUINONES (also known as anthraquinonoids) are a class of naturally occurring phenolic compounds based on the 9,10-anthraquinone skeleton, are the plant products Used in household/ traditional medicine for centuries. PHARMACODYNAMIC & FUNCTION:- senna is obtained from leaves and pods of certain cassia sp., While Cascara sagrada is the powdered bark of the buck - thorn tree. These and a number of other plant purgatives contain ANTHRAQUINONES glycosides, also called emodins. Senna is most popularly used. The glycosides are not active as such . Unabsorbed in the small intestine,they passed to the colon where bacteria liberate the active anthrol from ,which either acts locally or is absorbed into circulation excerted in bile to act on small intestine. Thus they take 6-8 hours produce action . Taken by lactating mothers,the amount secreted in milk is sufficient to cause purgation in the suc...