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ANASTROZOLE

To ANASTROZOLE BRAND NAME:- ALTRAZ,ARMOTRAZ ,ANABREZ 1mg tab. ANASTROZOLE   another nonsteroidal and reversible (type 2) aromatase inhibitors (AI) , more potent than letrozole and suitable from single daily dosing.  ACTION:- Anastrozole is an aromatase inhibitor. It works by lowering the amount of estrogen (natural female hormone) produced in the body. This can lower or stop the growth of some breast cancer cells that need estrogen to grow. It accumulates in the body to produce peak effects after 7-10 days . Anastrozole is useful as adjuvant therapy in early ER+ I've breast cancer as well as for palliation of advanced cases in postmenopausal women. In early cases, tumor recurrence time was found to be longer than with tamoxifen. Risk of new tumor appearing in the contralateral breast was also lower with anastrozole. A longer time to disease progression compared to tamoxifen has been obtained in advanced ER + ve breast cancer. Many tamoxifen resistance cases responded with...