BAMBUTEROL BRAND NAME:- BAMBUDIL 10mg ,20mg tabs ,5mg/5ml oral soln; BETADAY 10,20mg tabs. BAMBUTEROL is a bronchodilator. It works by relaxing the muscles in the airways and widens airways. This makes breathing easier. PHARMACODYNAMIC:- Bambuterol is a long acting beta2-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline. Bambuterol causes smooth muscle relaxation, resulting in dilation of bronchial passages. MECHANISM OF ACTION:- The pharmacologic effects of bambuterol are at least in part attributable to stimulation through beta-adrenergic receptors (beta 2 receptors) of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. USED:- used in the treatment of chronic obstructi...
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