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 Cimetidine  Brand name:- Cimetidine 200mg , 400mg , 800mg tabs, 200mg/2ml injection. , Lock-2 200mg tab. Cimetidine is a gastric acid reducer used in the short-term treatment of duodenal and gastric ulcers. [1] Therefore, the drug effectively manages gastric hypersecretion and is used to manage reflux esophagitis disease and prevent stress-related gastric ulcers. Pharmacodynamic:-  Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-r...