ARTEETHER BRAND NAME:- Artiz,Asth, Erod M etc. ARTEETHER is used for chloroquine resistant malaria, falciparum malaria and other cerebral malaria cases. It kills malarial parasites by interacting with heme.Arteether is an effective anti-malarial medicine . Arteether (i.m.) is slower acting than artesunate (i.v.) ,and appears to be less efficacious. It is used only in india. An injectable compound Arteether (i.m or i.v.) was produced in India in the 1990s. Pharmacodynamic:- In the body, artemether is metabolized into the active metabolite metabolite dihydroartemisinin. The drug works against the erythrocytic stages of P. falciparum by inhibiting nucleic acid and protein synthesis. Artemether is administered in combination with lumefantrine for improved efficacy. Artemether has a rapid onset of action and is rapidly cleared from the body. It is thought that artemether provides rapid symptomatic relief by reducing the number of malarial parasites. Lumefantrine has a much longer...
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