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 AMBROXOL BRAND NAME:- AMBRIL,AMBROLITE,AMBRODIL,MUCOLITE 30mg tab,30mg/5 ml liquid,7.5mg/ml drops. Ambroxol a metabolite of bromhexine having similar mucolytic action.The initiation of the action occurs after about 30 minutes when administered orally. The degradation of the fibers of acid mucopolysaccharide makes the sputum thinner and less viscous and therefore easier to extract by coughing. While sputum volume gradually decreases, for as long as care is continued, its viscosity remains low. MECHANISM OF ACTION:- Ambroxol is a mucolytic agent. Excessive Nitric oxide (NO) is associated with inflammatory and some other disturbances of airways function. NO enhances the activation of soluble guanylate cyclase and cGMP accumulation. Ambroxol has been shown to inhibit the NO-dependent activation of soluble guanylate cyclase. It is also possible that the inhibition of NO-dependent activation of soluble guanylate cyclase can suppress the excessive mucus secretion, therefore it lowers the...