BICUCLLINE BRAND NAME:- no specific brand available. BICUCLLINE is synthetic convulsant has picrotoxin - like action. It is a competitive GABAa receptor ( intrinsic CI- channel receptors) antagonist, while GABAb receptor ( G- protein couple receptor) is insensitive to it. It is only a research tool . PHARMACODYNAMIC:- Not available . MECHANISM OF ACTION:- Not available. USED:- Used for screening for AEDs as classical anticonvulsant drugs, and especially GABAA receptor-acting drugs, are effective in this model. SIDE EFFECTS:- Unknown. DOSE:- DIRECTION BY PHYSICIAN.
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