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 Carbamazepine Brand name:- Tegretol, Mazetol, Carbazole, Mazetol sr , Tegrital Cr 200,400mg tab. Carbamazepine is an anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia. Pharmacodynamic:-  General effects  Carbamazepine treats seizures and the symptoms of trigeminal neuralgia by inhibiting sodium channels. In bipolar  1 disorder, carbamazepine has been found to decrease mania symptoms in a clinically significant manner according to the Young Mania Rating Scale (YMRS).Carbamazepine has a narrow therapeutic index. A note on genetic variation and carbamazepine use In studies of Han Chinese ancestry patients, a pronounced association between the HLA-B*1502 genotype and Steven Johnson syndrome and/or toxic epidermal necrolysis (SJS/TEN) resulting from carbamazepine use was observed. Pharmacokinetics:-  Oral absorption of carbamazepine is slow and variable because of poor water solubility. It is 75% bound to plasma prot...