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 AZTREONAM BRAND NAME:- AZENAM ,TREZAM 0.5,1.0,2.0 g/ vial inj . AZTREONAM is a novel Beta- lactam antibiotic in which the other ring is missing (hence monobactam ) , but acts by binding to specific PBPs. It inhibits gram- negative enteric bacilli and H.influenzae . PHARMACOLOGY:-  it is a novel Beta-lactam antibiotic in which the other ring is missing ( hence monobactam), but acts by binding to specific PBPs . It inhibits gram-negative enteric bacilli and H. Influenzae at very low concentrations and pseudomonas at moderate concentration,but does not inhibits gram - positive cocci or faecal anaerobes. Thus ,it is a Beta - lactam antibiotic with a spectrum resembling aminoglycosides,and is resistant to gram - negative Beta - lactamases . The main indications of Aztreonam are hospital acquired infection originating from urinary, biliary, Gastrointestinal and female genital tracts .  MECHANISM OF ACTION:- Aztreonam is similar in action to penicillin. The bactericidal action ...