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 Ciprofloxacin Brand name:- Cifran , ciplox, ciprobid , ciprolet 250,500,750mg tab, 200mg/100ml i.v infusion, 3mg / ml eye drops. Ciprofloxacin  is a second generation fluoroquinolone used to treat various susceptible bacterial infections. Pharmacodynamic :-  Ciprofloxacin is a second generation fluoroquinolone that is active against many Gram negative and Gram positive bacteria. It produces its action through inhibition of bacterial DNA gyrase and topoisomerase IV. Ciprofloxacin binds to bacterial DNA gyrase with 100 times the affinity of mammalian DNA gyrase.There is no cross resistance between fluoroquinolones and other classes of antibiotics, so it may be of clinical value when other antibiotics are no longer effective. Ciprofloxain and its derivatives are also being investigated for its action against malaria, cancers, and AIDS. Pharmacokinetics:-  Ciprofloxacin is rapidly absorbed orally,but food delays absorption,and first pass metabolism occurs. Ciprofloxacin...