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BENAZEPRIL Uses, Side Effects, and More

 BENAZEPRIL BRAND NAME:- BENZIL,Apriace,BENACE 5,10,20mg tab. Benazepril is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.  PHARMACODYNAMIC:- Benazepril, an angiotensin-converting enzyme (ACE) inhibitor, is a prodrug which, when hydrolyzed by esterases to its active Benazeprilat, is used to treat hypertension and heart failure, to reduce proteinuria and renal disease in patients with nephropathies, and to prevent stroke, myocardial infarction, and cardiac death in high-risk patients. Benazepril and Benazeprilat inhibit angiotensin-converting enzyme (ACE) in human subjects and animals . ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex.  MECHANISM OF ACTION:-  Benazepril...

AMPICILLIN

 AMPICILLIN BRAND NAME:-AMPICLIN,ROSCILLIN,BIOCILIN 250mg cap; 125,250mg/5ml dry syr; 100mg/ ml pediatric drops ; 250,500mg and 1.0 g per vial inj. AMPICILLIN is a extended spectrum penicillins of Aminopenicillins group drug . It is active against all organisms sensitive to PnG . In addition,many gram-negative bacilli,e g H. Influenzae, E.coli, Proteus salmonella Shigella and Helicobacter pylori are inhibited. However,due to wide- spread use ,many of these have developed resistance ; usefulness of the antibiotics has decreased considerably. AMPICILLIN is more active than PnG for Strep. Viridans , enterococci and Listeria ; equally active for pneumococci , gonococci and meningococci ( penicillin - resistant strains are resistant to ampicillin as well); but less active against other gram- postive cocci. Penicillinase producing Staph. are not affected, as are other gram-negative bacilli,such as Pseudomonas, Klebsiella, indole positive Proteus and anaerobes like Bacteroides fragilis. P...