BENZODIAZEPINES ( BZDs) BRAND NAME:- No specific brand available BENZODIAZEPINES (BZDs) in addition to prea aesthetic medication,BNZs are now frequently used for including, maintaining and supplementing anaesthesia as well as for ' conscious sedation ' . PHARMACODYNAMIC:- UNKNOWN. PHARMACOLOGICAL ACTION:- The weak antiemetic property of BZDs is primarily based on the sedative action. Benzodiazepines work by increasing the effectiveness of the endogenous chemical, GABA, to decrease the excitability of neurons.This reduces the communication between neurons and, therefore, has a calming effect on many of the functions of the brain. GABA controls the excitability of neurons by binding to the GABA receptor. The GABAa receptor is a protein complex located in the synapses between neurons. All GABAa receptors contain an ion channel that conducts chloride ions across neuronal cell membranes and two binding sites for the neurotransmitter gamma-amino...
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