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 CYPROTERONE ACETATE (CPA) BRAND NAME:- GINETE -35 ,DINAC - 35 . CYPROTERONE ACETATE is a steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer. PHARMACODYNAMIC:-  CPA has antiandrogenic activity,progestogenic activity, weak partial glucocorticoid activity, weak steroidogenesis inhibitor activity, and agonist activity at the pregnane X receptor. It has no estrogenic or antimineralocorticoid activity. In terms of potency, CPA is described as a highly potent progestogen, a moderately potent antiandrogen, and a weak glucocorticoid.Due to its progestogenic activity, CPA has antigonadotropic effects, and is able to suppress fertility and sex-hormone levels in both males and females. PHARMACOKINETICS:- CPA can be taken by mouth or by injection into muscle. It has near-complete oral bioavailability, is highly and exclusively boun...