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 ACAMPROSATE BRAND NAME:-. CAMPRAL & other brands available. ACAMPROSATE is a medical use along with counseling to treat alcohol use disorders.  Acamprosate is thought to stabilize  chemical signaling in the brain  that would otherwise be disrupted by alcohol withdrawal. When used alone, acamprosate is not an effective therapy for  alcohol use disorder  in most individuals; studies have found that acamprosate works best when used in combination with psychosocial support since the drug facilitates a reduction in alcohol consumption as well as full abstinence. PHARMACOLOGICAL & MECHANISM OF ACTION:- It is a weak NMDA -receptor antagonist with modest GABAa receptor agonistic activity that is being used in USA ,UK and Europe for maintenance therapy of alcohol abstinence. In conjunction with social and motivational therapy,it has been found to reduce relapse of the drinking behaviour. The efficacy of ACAMPROSATE in this regard is rated comparable to nalt...