BEZAFIBRATE BRAND NAME:- BEZALIP 200,400mg tab. BEZAFIBRATE rate is a lipid lowering medication. It works by lowering the levels of triglycerides and "bad" cholesterol (LDL), while raising the levels of "good" cholesterol (HDL). PHARMACODYNAMIC:- This is second generation fibric acid derivatives is an alternative to gemfibrozil in mixed hyperlipidemias ( type III,IV and V ) . Though it has also been indicated in hypercholesterolemia ( type II) ,it is inferior to statins and resins . Bezafibrate has not shown propensity to increase LDL- CH in hypertriglyceridaemic patients and appears to have greater LDL- CH lowering action than gemfibrozil. Circulating fibrinogen and glucose levels may decrease. The 5 year ' Bezafibrate coronary Atherosclerosis Intervention Trail '( BECAIT) in young male post - MI subjects showed an atherosclerosis slowing effects and reduction in coronary events. The Bezafibrate infarction prevention (BIP) registry has also noted reducti...
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