CLOPIDOGREL BRAND NAME:- CLODREL, CLOPILET, DEPLATT 75mg tab. CLOPIDOGREL is an antiplatelet medicine or a blood thinner that helps to prevent the formation of harmful blood clots in your blood vessels. This helps to lower the chances of you getting a heart attack or stroke. It is a widely used medicine for heart protection. PHARMACODYANIMCS:- Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. It has a long duration of action as it is taken once daily and a large therapeutic window as it is given in doses of 75-300mg daily. MECHANISM OF ACTION:- Clopidogrel is metabolized to its active form by carboxylesterase-1.The active form is a platelet inhibitor that irreversibly binds to P2Y12 ADP receptors on platelets. This binding prevents ADP binding to P2Y12 receptors, activation of the glycoprotein GPIIb/IIIa complex, and platelet aggregation. USED:- Clopidogrel is used to prevent heart attacks an...
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