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AMISULPIRIDE

 AMISULPIRIDE BRAND NAME:- SULPITAC ,AMIPRIDE,ZONAPRIDE 50,100,200mg tabs. AMISULPIRIDE is an antiemetic and typical antipsychotic , m edication used at lower doses intravenously to prevent and treat postoperative nausea and vomiting. ACTION:- Amisulpiride  is a congener of sulpiride is categorized with the atypical antipsychotics because it produces few extra pyramidal side effects and improves many negative symptoms of schizophrenia as well. However,it retains high affinity for D2 and D3 receptors and has low-affinity for 5- HT 2 receptors. Hyperpolactinemia occurs similar to typical neuroleptics. Antidepressant property has been noted. Amisulpiride is not a sedative . USE:- Treatment of Acute and chronic schizophrenic disorders. Treatment of  postoperative nausea and vomiting. SIDE EFFECTS:- Rather, insomnia, anxiety and agitation. Risk of weight gain and metabolic complication is lower . DOSE:- 50-300mg/day in 2 doses for schizophrenia with predominant negative sympto...