carbetocin Uses, Side Effects, and More

 carbetocin

Brand name:- Pabal, Duratocin.

Carbetocin belongs to a class of medicines called oxytocin receptor agonists. Oxytocin is the hormone that helps in muscle contraction during labor. This medicine binds with oxytocin receptors present on the smooth muscles of the uterus and helps in muscle contractions. These rhythmic contractions of the uterus help in childbirth and prevent excessive bleeding after childbirth.

Pharmacodynamic:-

Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is sold under the trade name Duratocin. It is an analogue of oxytocin, and its action is similar to that of oxytocin; it causes contraction of the uterus. 

Mechanism of action:- 

Carbetocin binds to oxytocin receptors present on the smooth musculature of the uterus, resulting in rhythmic contractions of the uterus, increased frequency of existing contractions, and increased uterine tone. The oxytocin receptor content of the uterus is very low in the non-pregnant state, and increases during pregnancy, reaching a peak at the time of delivery.

Used:-

used in the treatment of Bleeding.

 Side effects:-

Nausea, Stomach pain, Itching, Headache, Flushing (sense of warmth in the face, ears, neck and trunk), Hypotension (low blood pressure), Tremors, Vomiting, Back pain, Chest pain, Metallic taste, Anemia (low number of red blood cells), Breathlessness, Chills, Generalized pain

 Dose:- As directed by your doctor.