CLARITHROMYCIN
BRAND NAME :- CLARIBID ,CLAIMAC, SYNCLAR
Pharmacodyanimcs:-
Clarithromycin is a macrolide antibiotic whose spectrum of activity includes many gram-positive (Staphylococcus aureus, S. pneumoniae, and S. pyogenes) and gram-negative aerobic bacteria (Haemophilus influenzae, H. parainfluenzae, and Moraxella catarrhalis), many anaerobic bacteria, some mycobacteria, and some other organisms including Mycoplasma, Ureaplasma, Chlamydia, Toxoplasma, and Borrelia. Other aerobic bacteria that clarithromycin has activity against include C. pneumoniae and M. pneumoniae. Clarithromycin has an in-vitro activity that is similar or greater than that of erythromycin against erythromycin-susceptible organisms. Clarithromycin is usually bacteriostatic, but may be bactericidal depending on the organism and the drug concentration.
mechanism of action :-
TARGET | ACTIONS | ORGANISM |
---|---|---|
A50S ribosomal protein L10 | inhibitor | Shigella flexneri |
UPotassium voltage-gated channel subfamily H member 2 | Not Available | Humans |
USolute carrier organic anion transporter family member 1B1 | Not Available | Humans |
USolute carrier organic anion transporter family member 1B3 | Not Available | Humans |
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