Chloroxylenol Uses, Side Effects, and More

 Chloroxylenol

Brand name:- Dettol,Dettolin 1% with menthol 0.45%

It has a phenol coefficient of 70; does not cosgulate proteins,is noncorrosive, nonirritating  to intact skin, but efficacy is reduced by oraganic matter. It is poorly water soluble; the commercial 4.8% solution (Dettol) is prepared in 9% terpinol and 13% alcohol.

Pharmacodynamic:-

Chloroxylenol is a substituted phenol which has been widely used for many years as an ingredient of antiseptic and disinfectant products intended for external use . It is known to be bactericidal in low concentration to a wide range of Gram positive and Gram negative bacteria .

Mechanics of action:- 

As a phenol antiseptic, it is believed that the hydroxyl -OH groups of the chloroxylenol molecule binds to certain proteins on the cell membrane of bacteria, and disrupts the membrane so as to allow the contents of the bacterial cell to leak out 1. This allows chloroxylenol to enter the bacterial cell to bind further with more proteins and enzymes to disable the cell's functioning 1. At particularly high concentrations of chloroxylenol, the protein and nucleic acid content of targeted bacterial cells become coagulated and cease to function, leading to rapid cell death.

Used:- 

Used for surgical antisepsis,to control bacteria, algae and fungi in adhesives, emulsions, paints and wash tanks. It also is used to sanitize bathroom premises, diaper pails, laundry equipment, human bedding and pet living quarters in households, hospitals and other institutions.

side effects:- 

Be careful when using this liquid, especially around kids as there is a high chance that kids might drink this liquid unknowingly.

Dose:- 

•Add 1-2 capful of Dettol to water for household cleaning activities.

•Use a few drops of Dettol to disinfect minor wounds and scrapes.

•Add 1 capful of Dettol to water while bathing.

•Add 1 capful of Dettol to your shaving mixture for a clean shave.

This antiseptic liquid is meant for external use ONLY.

(Keep it out of reach of children to avoid any casualty.)