Skip to main content

CYCLANDELATE Uses, Side Effects, and More

 CYCLANDELATE 

BRAND NAME:- CYCLOSPASMOL, CYCLASYN 200,400mg tab/cap.

CYCLANDELATE is a papacrine like general smooth muscle relaxant which increases cutaneous, seketal muscle and cranial blood flow in normal individ.However, efficacy in PVDs is not different from placebo. 

PHARMACODYANAMICS:-

Cyclandelate is in a class of drugs called vasodilators. Cyclandelate relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.

 MECHANISM OF ACTION:- 


Cyclandelate produces peripheral vasodilation by a direct effect on vascular smooth muscle. Pharmacological action may be due to calcium-channel antagonism.


USED:- 

Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.

SIDE EFFECTS:- 

Flushing , palpitations and headaches. 

DOSE:- 200-400mg TDS; OR as directed by your Doctor. 

Comments

Popular posts from this blog

Know details about Dabigatran etexilate drug ?

 Dabigatran Etexilate 

Chlorthalidone Uses, Side Effects, and More....

 Chlorthalidone  Brand name:- Hythalton 50,100mg , Hydrazide, Thalizide ( 12.5, 25) . Chlorthalidone is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Pharmacodynamic:- Not 🚫 available.  Pharmacokinetics:- Chlortalidone is slowly absorbed from the gastrointestinal tract after oral ingestion. It has a long half-life and therefore a prolonged diuretic action, which results in continued diuretic effects despite a skipped dose. This prolonged action of chlortalidone despite missing doses may account for the higher efficacy of chlortalidone compared to the shorter half-life medication, hydrochlorothiazide. Chlortalidone is eliminated from the body mostly by the kidney, as unchanged drug. Thus, in persons with diminished kidney function, the clearance of chlortalidone is reduced and the elimination half-life is increased. As with other thiazide diuretics, ch...

Danaparoid : used, mechanism of action, pharmacodynamic | webmedi.blogspot.com

 Danaparoid