CYCLANDELATE
BRAND NAME:- CYCLOSPASMOL, CYCLASYN 200,400mg tab/cap.
CYCLANDELATE is a papacrine like general smooth muscle relaxant which increases cutaneous, seketal muscle and cranial blood flow in normal individ.However, efficacy in PVDs is not different from placebo.
PHARMACODYANAMICS:-
Cyclandelate is in a class of drugs called vasodilators. Cyclandelate relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.
MECHANISM OF ACTION:-
Cyclandelate produces peripheral vasodilation by a direct effect on vascular smooth muscle. Pharmacological action may be due to calcium-channel antagonism.
USED:-
Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.
SIDE EFFECTS:-
Flushing , palpitations and headaches.
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