BAMBUTEROL Uses, Side Effects, and More

BAMBUTEROL

BRAND NAME:- BAMBUDIL 10mg ,20mg tabs ,5mg/5ml oral soln; BETADAY 10,20mg tabs.

BAMBUTEROL is a bronchodilator. It works by relaxing the muscles in the airways and widens airways. This makes breathing easier.

PHARMACODYNAMIC:-

Bambuterol is a long acting beta2-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline. Bambuterol causes smooth muscle relaxation, resulting in dilation of bronchial passages.

MECHANISM OF ACTION:-

The pharmacologic effects of bambuterol are at least in part attributable to stimulation through beta-adrenergic receptors (beta 2 receptors) of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.

USED:-

used in the treatment of chronic obstructive pulmonary disease.

SIDE EFFECTS:-

Headache, Restlessness, Insomnia (difficulty in sleeping), Palpitations, Trembling, Muscle cramp.

DOSE:- DIRECTED BY YOUR DOCTOR & PHYSICIAN.

Chlorthalidone Uses, Side Effects, and More....

Chlorthalidone Brand name:- Hythalton 50,100mg , Hydrazide, Thalizide ( 12.5, 25) . Chlorthalidone is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Pharmacodynamic:- Not 🚫 available. Pharmacokinetics:- Chlortalidone is slowly absorbed from the gastrointestinal tract after oral ingestion. It has a long half-life and therefore a prolonged diuretic action, which results in continued diuretic effects despite a skipped dose. This prolonged action of chlortalidone despite missing doses may account for the higher efficacy of chlortalidone compared to the shorter half-life medication, hydrochlorothiazide. Chlortalidone is eliminated from the body mostly by the kidney, as unchanged drug. Thus, in persons with diminished kidney function, the clearance of chlortalidone is reduced and the elimination half-life is increased. As with other thiazide diuretics, ch...

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