BACITRACIN Uses, Side Effects, and More

 BACITRACIN

BRAND NAME:- NEBASULF ,NEOSPORIN 400U/g powder.

BACITRACIN is an antibiotic ointment that's used to help prevent skin infections in small cuts, scrapes, and burns. It's not meant to treat animal bites, serious burns, or deep puncture wounds - those might require medical attention. It's available over the counter (OTC) and as a less expensive, generic medication.

PHARMACODYNAMIC:- 

Bacitracin is a mixture of polypeptides that prevent the formation of the bacterial cell wall and oxidatively cleave DNA. It has a short duration of action as it must be given every 3 to 4 hours topically. Bacitracin is nephrotoxic when given intramuscularly and may lead to renal failure.

MECHANISM OF ACTION:-

Bacitracin interferes with the dephosphorylation of C55- isoprenyl pyrophosphate, and a related molecule known as bactoprenol pyrophosphate; both of these lipids function as membrane carrier molecules that transport the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane.

 USE:- 

Preventing bacterial infections in minor cuts, scrapes, and burns.

SIDE EFFECTS:- 

itching.

rash.

hives.

difficulty breathing or swallowing.

DOSE:-  DIRECTION BY PHYSICIAN.