BUSPIRONE
BRAND NAME:- ANXIPAR,BUSPIN,BUSCALM 5,10mg tab.
BUSPIRONE is the first azapirone,a new class of antianxiety drug,distinctly different from BZDs.
PHARMACODYNAMIC :-
Buspirone is an anxiolytic drug given at a dosage of 15 mg/day. The mechanism of action of the drug is not well characterised, but it may exert its effect by acting on the dopaminergic system in the central nervous system or by binding to serotonin (5-hydroxytryptamine) receptors.
MECHANISM OF ACTION:-
Buspirone (Buspar) is a azaspirodecanedione anxiolytic agent. Its mechanism of action is extremely complex, but current investigations indicate that its main neuropharmacologic effects are mediated by the 5-HT1A receptors. Other neuroreceptor systems could be involved, as buspirone displays some affinity for DA2 autoreceptors and 5-HT2 receptors.
USED:-
used to treat anxiety.
SIDE EFFECTS:-
Dizziness, drowsiness, headache, nausea, nervousness, lightheadedness, restlessness, blurred vision, tiredness, and trouble sleeping may occur.
DOSE:- 5-15mg OD-TDS
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