BROMHEXINE

 BROMHEXINE

BRAND NAME:- BROMHEXINE 8mg tablet,4mg/5ml elixer.

BROMHEXINE is a derivative of the alkaloids vasicine obtained from Adhatoda vasica (Vaska), is a potent mucolytic and mucokinetic , capable of inducing thin copious bronchial secertion.

PHARMACODYNAMIC:-

Bromhexine thins airway secretions, improving breathing and discomfort associated with thick mucus in airways associated with a variety of respiratory conditions .

MECHANISM OF ACTION:-

BROMHEXINE is a mucolytic agent that act on the mucus glands in the respiratory tract to change the structure of  bronchial secertion . It enhances the transport of  mucus by reducing its viscosity and increase cilia activity resulting in enhances mucocilliary clearance. This secretolytic and secretomotor effects in the bronchial tract  facilitates expectoration and relives  cough.

USED:-

Bromhexine is used in the treatment of respiratory tract disorders associated with viscid mucus. 

SIDE EFFECTS:-

Dizziness, Headache, Nausea, Upper abdominal pain, Vomiting, Diarrhea, Rash, Red spots or bumps, Itching, Sweating, Changes in serum aminotransferase levels

DOSE:- Adults 8mg TDS, children 1-5 years 4mg BD ,5-10yeras 4mg TDS.