Skip to main content

BISOPROLOL used, dose , brand name & more...

 BISOPROLOL

BRAND name:- CONCOR ,CORBIS 5mg tab 

BISOPROLOL is a Cardioselective Beta blockers lacking intrinsic sympathomimetics activity; suitable for once daily administration in angina, hypertension and CHF.

PHARMACODYNAMIC:-

Bisoprolol decreases heart rate (chronotropy), decreases contractility (inotropy), and reduces blood pressure. The results of various clinical studies indicate that bisoprolol reduces cardiovascular mortality and all-cause mortality in patients with heart failure and decreased cardiac ejection fraction (EF).

MECHANISM of action:-

Bisoprolol is cardioprotective because it selectively and competitively blocks catecholamine (adrenaline) stimulation of β1 adrenergic receptors (adrenoreceptors), which are mainly found in the heart muscle cells and heart conduction tissue (  cardiospecific )  but also found in juxtaglomerular cells in the kidney. It works by relaxing blood vessels and slowing heart rate to improve and decrease blood pressure. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. 

USE:-

Used  in the treatment of  Hypertension, Angina, Arrhythmias , myocardial infraction and migraine.

SIDE EFFECTS:-

fatigue, hypotension, hypoglycemia, bronchospasms, and bradycardia.Bronchospasms and hypoglycemia occur because at high doses.


DOSE:- ½ to 2 tab OD, As directed by your doctor.

Labels:

Comments

Post a Comment

Popular posts from this blog

Chlorthalidone Uses, Side Effects, and More....

 Chlorthalidone  Brand name:- Hythalton 50,100mg , Hydrazide, Thalizide ( 12.5, 25) . Chlorthalidone is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Pharmacodynamic:- Not 🚫 available.  Pharmacokinetics:- Chlortalidone is slowly absorbed from the gastrointestinal tract after oral ingestion. It has a long half-life and therefore a prolonged diuretic action, which results in continued diuretic effects despite a skipped dose. This prolonged action of chlortalidone despite missing doses may account for the higher efficacy of chlortalidone compared to the shorter half-life medication, hydrochlorothiazide. Chlortalidone is eliminated from the body mostly by the kidney, as unchanged drug. Thus, in persons with diminished kidney function, the clearance of chlortalidone is reduced and the elimination half-life is increased. As with other thiazide diuretics, ch...
Post a Comment
Read more

Chlordiazepoxide Uses, Side Effects, and More

 Chlordiazepoxide Brand name:- Librium 10, 25 mg tabs; Equilibrium 10mg tab. Chlordiazepoxide is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain. Pharmacodynamic:-  Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The drug seems to block EEG arousal from stimulation in the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dos...
Post a Comment
Read more

Know details about Dabigatran etexilate drug ?

 Dabigatran Etexilate 
Post a Comment
Read more