BISOPROLOL used, dose , brand name & more...

 BISOPROLOL

BRAND name:- CONCOR ,CORBIS 5mg tab 

BISOPROLOL is a Cardioselective Beta blockers lacking intrinsic sympathomimetics activity; suitable for once daily administration in angina, hypertension and CHF.

PHARMACODYNAMIC:-

Bisoprolol decreases heart rate (chronotropy), decreases contractility (inotropy), and reduces blood pressure. The results of various clinical studies indicate that bisoprolol reduces cardiovascular mortality and all-cause mortality in patients with heart failure and decreased cardiac ejection fraction (EF).

MECHANISM of action:-

Bisoprolol is cardioprotective because it selectively and competitively blocks catecholamine (adrenaline) stimulation of β1 adrenergic receptors (adrenoreceptors), which are mainly found in the heart muscle cells and heart conduction tissue (  cardiospecific )  but also found in juxtaglomerular cells in the kidney. It works by relaxing blood vessels and slowing heart rate to improve and decrease blood pressure. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. 

USE:-

Used  in the treatment of  Hypertension, Angina, Arrhythmias , myocardial infraction and migraine.

SIDE EFFECTS:-

fatigue, hypotension, hypoglycemia, bronchospasms, and bradycardia.Bronchospasms and hypoglycemia occur because at high doses.

DOSE:- ½ to 2 tab OD, As directed by your doctor.