Skip to main content

Cefdinir Uses, Side Effects, and More

 Cefdinir

Brand name:- Sefdin , Adcef 300mg cap.

Cefdinir is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Pharmacodynamic:- 


Cefdinir is a bactericidal agent that treats bacterial infections by interfering with cell wall synthesis. Cefdinir exerts broad-spectrum activity against a variety of gram-positive and gram-negative bacterial infections. It is effective against several beta-lactamase enzyme producing bacteria. As a result, many organisms that are resistant to other cephalosporins may be susceptible to cefdinir.

Mechanism of action:- 

Cefdinir are bactericidal and, like other β-lactam antibiotics, disrupt the synthesis of the peptidoglycan layer forming the bacterial cell wall. The peptidoglycan layer is important for cell wall structural integrity. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Beta-lactam antibiotics mimic the D-Ala-D-Ala site, thereby irreversibly inhibiting PBP crosslinking of peptidoglycan.

used:- 

Used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic.

Side effects:- 

Diarrhea, headache, or nausea Vaginal moniliasis, Abdominal pain, Vaginal inflammation, Protein in urine, Increased gamma-glutamyltransferase, High lymphocyte count, Lymphocytopenia, Microhematuria, Increased urine leukocyte .

Dose:- 300mg OD , as directed by your doctor.


Comments

Popular posts from this blog

Know details about Dabigatran etexilate drug ?

 Dabigatran Etexilate 

Know details learn about DACARBAZINE ( DTIC) ?

DACARBAZINE  (DTIC)

Calcium Uses, Side Effects, and More

 Calcium Brand name:- calcinol, cipcal ,M ilical, Calcium sandoze, Shelcal ,  Macalvit . Calcium is a mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency.  PREPARATION:-  1. Calcium carbonate (40% Ca) : It is an insoluble, tasteless and nonirritating salt. Reacts with gastric HCL  to form cholride, and can be used as antacid. It is the most common salt present in calcium supplements, but gastric acid is required for  converting it into the absorbable form . Calcium availability from it is poor in patients taking proton pump inhibitors (PPIs) ,H² blocker, and in elderly. 2.  Calcium citrate ( as tetrahydrate , 21% Ca²+ ) : Slightly soluble in water, but dissolve well in presence of HCL . It is nonirritating and is used in supplements; absorption in patients taking PPIs/H² blocker and elderly is satisfactory. 3. Calcium gluconate (9% Ca) : is availa...