Carbachol Uses, Side Effects, and More

 Carbachol 

Brand name:- Miostat.

Carbachol, also known as carbamylcholine and sold under the brand name Miostat among others, is a cholinomimetic drug that binds and activates acetylcholine receptors. Thus it is classified as a cholinergic agonist. It is primarily used for various ophthalmic purposes, such as for treating glaucoma, or for use during ophthalmic surgery. It is generally administered as an ophthalmic solution (i.e., eye drops).

Pharmacodynamic:- 

Carbamoylcholine is a parasympathomimetic that acts as an agonist of muscarinic and nicotinic receptors. It is more resistant to hydrolysis by acetylcholinesterase than other choline esters leading to a longer duration of action, with significant effects 24 hours after administration.5 Data regarding the therapeutic index of carbamoylcholine is not readily available. Patients should be counselled regarding the risk of administering the drug to patients with acute cardiac failure, bronchial asthma, peptic ulcer, hyperthyroidism, gastrointestinal spasm, urinary tract obstruction, or Parkinson's disease.

Mechanism of action:- 

Cholinergic drugs constrict the pupillary sphincter, tighten the iris, decrease the volume of iris tissue in the angle, and pull the peripheral iris away from the trabecular meshwork. These changes reduce intraocular pressure (IOP) by allowing aqueous humor to reach the outflow channels.

Used:- 

used in the treatment of glaucoma.

Side effects:- 

Common side effects of Carbachol include:

Blurred vision,flushing (warmth, redness, or tingly feeling),stomach pain,headache, and a tight feeling in your bladder.

Dose:- AS Directed by your doctor.