Cyclopentolate
BRAND NAME:- CYLOMID EYE 0.5% , CYCLOGYL, CYCLOPENT 1%
Cyclopentolate is an anticholinergic , is potent and rapidly acting ; mydriasis and cycloplegia occur in 30 -60min and last about a day. It is preferred for cycloplegic refraction, but children may show tranisent behavioural abnormalities due to absorption of the drug after passage into the nasolacrimal duct. It is also used in iritis and uveitis.
PHARMACODYNAMICS:-
Cyclopentolate is an anti-muscarinic in the same class as atropine and scopolamine. Cyclopentolate blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. Cyclopentolate thus induces relaxation of the sphincter of the iris and the ciliary muscles. When applied topically to the eyes, it causes a rapid, intense cycloplegic and mydriatic effect that is maximal in 15 to 60 minutes; recovery usually occurs within 24 hours. The cycloplegic and mydriatic effects are slower in onset and longer in duration in patients who have dark pigmented irises.
MECHANISM OF ACTION:-
By blocking muscarinic receptors, cyclopentolate produces dilatation of the pupil (mydriasis) and prevents the eye from accommodating for near vision (cycloplegia).
USED:-
Used as an eye drop during pediatric eye examinations to dilate the eye (mydriatic) and prevent the eye from focusing/accommodating (cycloplegic).
SIDE EFFECTS:-
Burning/stinging/redness of the eye, eye irritation, or temporary blurred vision may occur.
DOSE:-
As Directed by your doctor.
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