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BACAMPICILLIN Uses, Side Effects, and More

 BACAMPICILLIN


BRAND NAME:- PENGLOBE 200,400mg tab.

BACAMPICILLIN is an ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections.

PHARMACODYNAMIC:- 

Bacampicillin is a prodrug of ampicillin and is microbiologically inactive.


MECHANISM OF ACTION:- 

BACAMPICILLIN acts by binding to specific penicillin  binding protein (PBPs)  located inside the bacterial cell wall , BACAMPICILLIN  is also said to inhibits the third or last stage bacterial cell wall synthesis. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides .


USED:- 

used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections .


SIDE EFFECTS:- 

gastrointestinal disturbances, rash, and hypersensitivity reactions. Gastrointestinal effects include, nausea, vomiting, anorexia, diarrhea, and gastritis.


DOSE:- 400-800mg BD .

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