BORIC ACID
BRAND NAME:- BORIC ACID, BOROCIDE
BORIC ACID Is only bacteriostatic and a very weak antiseptic. But being non irritating even to delicate structure, saturated aqueous solution (4%) have been used for irrigating eyes , mouth wash ,douche, etc.
PHARMACODYNAMIC:-
Boric acid exhibits minimal bacteriostatic and antifungal activities 4. Boric acid is likely to mediate antifungal actions at high concentrations over prolonged exposures.
MECHANISM OF ACTION:
Information regarding the mechanism of action of boric acid in mediating its antibacterial or antifungal actions is limited. Boric acid inhibits biofilm formation and hyphal transformation of Candida albicans, which are critical virulence factors . In addition, arrest of fungal growth was observed with the treatment of boric acid .
USED:-
Its use for irrigating bladder,large wounds ,as ointment on extensive burnt areas,liberal use of powder for infants is not recommended.
SIDE EFFECTS:-
Boric acid is not innocuous; systemic absorption causes vomiting, abdominal pain, Diarrhoea, visual disturbances and kidney damage.
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