BORIC ACID Uses, Side Effects, and More

BORIC ACID

BRAND NAME:- BORIC ACID, BOROCIDE

BORIC ACID Is only bacteriostatic and a very weak antiseptic. But being non irritating even to delicate structure, saturated aqueous solution (4%) have been used for irrigating eyes , mouth wash ,douche, etc.

PHARMACODYNAMIC:-

Boric acid exhibits minimal bacteriostatic and antifungal activities 4. Boric acid is likely to mediate antifungal actions at high concentrations over prolonged exposures.

MECHANISM OF ACTION:

Information regarding the mechanism of action of boric acid in mediating its antibacterial or antifungal actions is limited. Boric acid inhibits biofilm formation and hyphal transformation of Candida albicans, which are critical virulence factors . In addition, arrest of fungal growth was observed with the treatment of boric acid .

USED:-

Its use for irrigating bladder,large wounds ,as ointment on extensive burnt areas,liberal use of powder for infants is not recommended.

SIDE EFFECTS:-

Boric acid is not innocuous; systemic absorption causes vomiting, abdominal pain, Diarrhoea, visual disturbances and kidney damage.

DOSE:- DIRECTION BY PHYSICIAN.

Chlorthalidone Uses, Side Effects, and More....

Chlorthalidone Brand name:- Hythalton 50,100mg , Hydrazide, Thalizide ( 12.5, 25) . Chlorthalidone is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Pharmacodynamic:- Not 🚫 available. Pharmacokinetics:- Chlortalidone is slowly absorbed from the gastrointestinal tract after oral ingestion. It has a long half-life and therefore a prolonged diuretic action, which results in continued diuretic effects despite a skipped dose. This prolonged action of chlortalidone despite missing doses may account for the higher efficacy of chlortalidone compared to the shorter half-life medication, hydrochlorothiazide. Chlortalidone is eliminated from the body mostly by the kidney, as unchanged drug. Thus, in persons with diminished kidney function, the clearance of chlortalidone is reduced and the elimination half-life is increased. As with other thiazide diuretics, ch...

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