Skip to main content

BETAMETHASONE

 BETAMETHASONE 



BRAND NAME:- BETNESOL ,BETACORTRIL ,CELESTONE 0.5mg ,1mgtab,BETNELAN 0.5mg ,1mg tabs. 


BETAMETHASONE is a steroid (also called a corticosteroid). Steroids help to reduce inflammation in the skin (and other parts of your body). Skin gets inflamed when an allergic reaction or irritation causes chemicals to be released in the skin. 


PHARMACOLOGY:-

Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. 


MECHANISM OF ACTION:-

Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. It has anti-inflammatory activity and can suppress the immune system. Corticosteroids can also stop skin cells from growing and multiplying.




USED:- 

Used in inflammatory and allergic conditions. For shock, cerebral edema.


DOSE:- 0.5 - 5mg/day oral, 4-20mg  i. m., i.v injection or infusion,also topical .


SIDE EFFECTS:-

skin irritation ,thinning of the skin where you will apply betamethasone,cataracts or glaucoma,diabetes,liver disease,adrenal gland problems; orany type of skin infection.



Labels:

Comments

Post a Comment

Popular posts from this blog

Know details about Dabigatran etexilate drug ?

 Dabigatran Etexilate 
Post a Comment
Read more

Chlorthalidone Uses, Side Effects, and More....

 Chlorthalidone  Brand name:- Hythalton 50,100mg , Hydrazide, Thalizide ( 12.5, 25) . Chlorthalidone is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Pharmacodynamic:- Not 🚫 available.  Pharmacokinetics:- Chlortalidone is slowly absorbed from the gastrointestinal tract after oral ingestion. It has a long half-life and therefore a prolonged diuretic action, which results in continued diuretic effects despite a skipped dose. This prolonged action of chlortalidone despite missing doses may account for the higher efficacy of chlortalidone compared to the shorter half-life medication, hydrochlorothiazide. Chlortalidone is eliminated from the body mostly by the kidney, as unchanged drug. Thus, in persons with diminished kidney function, the clearance of chlortalidone is reduced and the elimination half-life is increased. As with other thiazide diuretics, ch...
Post a Comment
Read more

Captopril Uses, Side Effects, and More

 Captopril Brand name:- Angiopril 25mg tab, Aceten, Captopril 12.5, 25mg tab. Captopril is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently. Pharmacodynamic:-  Captopril, an ACE inhibitor, antagonizes the effect of the RAAS. The RAAS is a homeostatic mechanism for regulating hemodynamics, water and electrolyte balance. During sympathetic stimulation or when renal blood pressure or blood flow is reduced, renin is released from the granular cells of the juxtaglomerular apparatus in the kidneys. In the blood stream, renin cleaves circulating angiotensinogen to ATI, which is subsequently cleaved to ATII by ACE. ATII increases blood pressure using a number of mechanisms. First, it stimulates the secretion of aldosterone from the adrenal cortex. Aldosterone travels to the distal convoluted tubule (DCT) and collecting tubule of nephrons w...
Post a Comment
Read more